주요토픽    인사말    프로테오글리칸    비변성Ⅱ형콜라겐    회사소개    공지&문의
 
현재위치: > 게시판 > 공지사항
공지사항
연어코연골추출물(NPG_프로테오글리칸 함유 85%이상) 및 연어코연골추출물(ACL-Ⅱ_비변성Ⅱ형콜라겐 함유 75%이상)관련 최신정보입니다.


찾기
제목 프로테오글리칸의 EGF작용과 관련한 논문개요 0  추천하기
작성자 관리자 작성일 2016-03-02 11:25:00 조회수 59
   
 

 http://www.ncbi.nlm.nih.gov/pubmed/8621059

Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function.

Abstract

This review focuses on the extracellular proteoglycans. Special emphasis is placed on the structural features of their protein cores, their gene organization, and their transcriptional control. A simplified nomenclature comprising two broad groups of extracellular proteoglycans is offered: the small leucine-rich proteoglycans or SLRPs, pronounced "slurps, " and the modular proteoglycans. The first group encompasses at least five distinct members of a gene family characterized by a central domain composed of leucine-rich repeats flanked by two cysteine-rich regions. The second group consists of those proteoglycans whose unifying feature is the assembly of various protein modules in a relatively elongated and often highly glycosylated structure. This group is quite heterogeneous and includes a distinct family of proteoglycans, the "hyalectans," that bind hyaluronan and contain a C-type lectin motif that is likely to bind carbohydrates, and a less distinct group that contains structural homologies but lacks hyaluronan-binding properties or lectin-like domains.

댓글달기 관리자에게만 댓글 작성 권한이 있습니다.
첨부파일
비밀번호 * 삭제하려면 비밀번호를 입력하세요.
수정
  스팸신고 스팸해제
글쓰기
 
이전글 당뇨병성 신증에 있어서 프로테오글리칸의 역할(논문)
다음글 프로테오글리칸의 항염작용 관련 논문개요
 
 
top